P05.18 Comparison of N-acetylaspartate concentration decrease in hippocampal and white brain tissue after whole brain radiotherapy
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چکیده
منابع مشابه
Dosimetric comparison of two different whole brain radiotherapy techniques in patients with brain metastases: How to decrease lens dose?
Background: Palliative whole brain radiotherapy (WBRT) has been the standard treatment for brain metastases. Ionizing radiation is known to be one of the most potent cataractogenic agents. We aimed to evaluate two different radiotherapy techniques with respect to the doses received by the organs at risk (OAR) in patients with brain metastasis who undergone WBRT. Materials and Methods: Ten conse...
متن کاملWhole-Brain N-Acetylaspartate Concentration Comparison of Young and Elderly Healthy: Evidence for Brain Durability
Introduction: An estimated 40 million Americans are currently 65 years of age or older, with that number expected to grow to 70 million by 2030 (1). Since several neurological conditions, especially Alzheimer’s Disease (AD) and the broad spectrum of ischemic disorders, afflict the elderly, the burden of these diseases to healthcare delivery will soon become staggering. Although it has been show...
متن کاملLongitudinal whole-brain N-acetylaspartate concentration in healthy adults.
BACKGROUND AND PURPOSE Although NAA is often used as a marker of neural integrity and health in different neurologic disorders, the temporal behavior of WBNAA is not well characterized. Our goal therefore was to establish its normal variations in a cohort of healthy adults over typical clinical trial periods. MATERIALS AND METHODS Baseline amount of brain NAA, Q(NAA), was obtained with nonloc...
متن کاملSerial whole-brain N-acetylaspartate concentration in healthy young adults.
Although the concentration of N-acetylaspartate (NAA) is often used as a neuronal integrity marker, its normal temporal variations are not well documented. To assess them over the 1-2 year periods of typical clinical trials, the whole-brain NAA concentration was measured longitudinally, over 4 years, in a cohort of healthy young adults. No significant change (adjusted for both sex and age) was ...
متن کاملdosimetric comparison of two different whole brain radiotherapy techniques in patients with brain metastases: how to decrease lens dose?
background: palliative whole brain radiotherapy (wbrt) has been the standard treatment for brain metastases. ionizing radiation is known to be one of the most potent cataractogenic agents. we aimed to evaluate two different radiotherapy techniques with respect to the doses received by the organs at risk (oar) in patients with brain metastasis who undergone wbrt. materials and methods: ten conse...
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ژورنال
عنوان ژورنال: Neuro-Oncology
سال: 2018
ISSN: 1522-8517,1523-5866
DOI: 10.1093/neuonc/noy139.344